Read more about Barcelona.
Flights from Barcelona to LyonThere are frequent flights from Barcelona to Lyon. This will be much quicker and probably cheaper than any other form of transport, as long as you book well in advance.
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Barcelona to Lyon by TrainThere are no direct trains from Barcelona to Lyon. You have to change in Montpellier.
Trains from Barcelona to Lyon (via Montpellier) depart from both Barcelona Franca and Sants station. Read more about Bus and Train Stations in Barcelona
Renfe.es, Spain's official rail website, is a mess and has been described as "like Alice in Wonderland, where nothing seems to be what it really is" by Trip Advisor. Residents of Canada and USA should use Rail Europe instead to have their tickets delivered to their home address. Other citizens should also use the link below to check timetables and then buy tickets in person.
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Barcelona to Lyon by BusThe bus from Barcelona to Lyon takes about nine hours and costs under 70 euros.
Buses from Barcelona to Lyon depart from both Sants and Nord bus stations. Read more about Bus and Train Stations in Barcelona
You can book most bus tickets in Spain online for a very small surcharge (two euros). Just pay with a credit card and print out the e-ticket - much easier than standing in line at the bus station.
Book Bus Tickets in Spain
The same ticket can be booked with Eurolines, but Movelia is easier to use.